Clinical application of nuclear medicine imaging in amyotrophic lateral sclerosis
10.3760/cma.j.issn.2095-2848.2014.03.027
- VernacularTitle:核医学影像在肌萎缩侧索硬化临床研究中的应用
- Author:
Peng FU
;
Lingge WEI
;
Ainan GUO
- Publication Type:Journal Article
- Keywords:
Amyotrophic lateral sclerosis;
Tomography,emission-computed,single-photon;
Tomography,emission-computed;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2014;34(3):253-256
- CountryChina
- Language:Chinese
-
Abstract:
Amyotrophic lateral sclerosis (ALS),a neurodegenerative disorder,is subtle in disease onset,difficult to diagnose,and fast-growing at progression.There.are at present little specific neurological imaging characteristics of ALS.Functional brain imaging techniques,such as SPECT and PET,were the early tools for investigation of ALS.The application of pixel-based analysis software (such as SPM) renders research in this area more convenient and objective.In recent years,improvement in brain receptor PET imaging has demonstrated its important value in the early diagnosis of ALS and evaluation of cognitive impairment.