Clinical observation of Aidi injection on imporving quality of life of the elderly and infirm patients with advanced cancer

Yuxian Yang; Zhiming Chen; Shuyao Zhang; Danxia Lin; Shengqi Zhang; Xiaowen Zhuang

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Clinical observation of Aidi injection on imporving quality of life of the elderly and infirm patients with advanced cancer

VernacularTitle:艾迪注射液改善年老体弱晚期癌症患者生活质量的临床观察
Author: Yuxian YANG ; Zhiming CHEN ; Shuyao ZHANG ; Danxia LIN ; Shengqi ZHANG ; Xiaowen ZHUANG
Publication Type:Journal Article
Keywords: Aidi injection; Advanced cancer; Cancer pain; Quality of life; Curative effect
From: Cancer Research and Clinic 2014;26(5):325-327
CountryChina
Language:Chinese
Abstract: Objective To evaluate the effects of Aidi injection on the short-term curative effect,pain level,quality of life and the survival time for the elderly and infirm patients with advanced cancer.Methods A total of 143 elderly patients with advanced cancer were randomly divided into two groups,71 patients in control group were treated with routine support therapies,and 72 patients in treatment group were injected with 50-60 ml Aidi injection infused in NS 250 ml by i.v drip every day combined with routine medicines,each cycle was 21 days,all patients were received for 2 cycles.Results After treatment the short-term curative effect rate (CR+PR) was 2.8 ％ (2/72) only compared with no effect of control group.But the effective and stabilization rate (CR+PR+SD) was 66.7 ％ (48/72),it was 31.0 ％ (22/71) in control group.There was significant difference between the two groups (P ＜ 0.05).The overall effective rate of easement of pain was 67.7 ％ (48/72) in treatment group versus 36.1％ (13/36) in control group (P ＜ 0.05).The median survival time (MST) was 6.2 months in treatment group versus 5.1 months in control group (P ＞ 0.05).The quality of life in treatment group was improved obviously (P ＜ 0.05).The side effects of patients in treatment group were very slight.Conclusions Aidi injection can reduce the cancer pain,improve the quality of life and prolong the survival time of the elderly and infirm patients with advanced cancer.It is safe,and effective to inhibit growth of tumor.It can be recommended widely to clinical use.