Clinical application of the multimodality treatment of brain arteriovenous malformation with Onyx embolization and microsurgery

VernacularTitle:Onyx介入栓塞联合显微手术切除脑动静脉畸形的临床应用
Author: Shaolei GUO ; Tiewei QI ; Feng LIANG ; Lingyan WANG ; Kejun HE ; Yibing YANG ; Zhengsong HUANG
Publication Type:Journal Article
Keywords: Brain arteriovenous malformation (BAVM); Onyx; Embolization; Microsurgical operation
From: Chinese Journal of Microsurgery 2014;37(3):250-253
CountryChina
Language:Chinese
Abstract: Objective To evaluate the clinical application of multimodality treatment of brain arteriovenous malformation (BAVM) with Onyx embolization and microsurgery.Methods There were 48 patients with BAVM treated by combination of Onyx embolization and microsurgery.The clinical features,therapeutic process,complications and discharge status (by MRI,DSA and Glasgow outcome scale,GOS) were recorded in detail.The prognosis was estimated by modified Rankin scale (mRS) with 6-42 months' follow-up.Results The total resection rate was 97.9％.The therapy-related complications happened in 8 patients (16.7％).Among them,4 cases had dysfunction of central nervous system (8.3％),2 cases with intra-cerebral hemorrhage (4.2％),and 2 suffered from severe cerebral edema (4.2％).Good recovery was seen in 38 cases (79.2％) evaluated by GOS when discharged from hospital.The follow-up result mRS ＜ 3 was 97.9％.Conclusion Multimodality treatment of BAVM with Onyx embolization and microsurgery should be a good therapeutic strategy.