Review of seven cases of neurobrucellosis: clinical manifestations and imaging characteristics
10.3760/cma.j.issn.1006-7876.2014.07.010
- VernacularTitle:神经型布氏杆菌病七例临床及影像学特点分析
- Author:
Meixi LI
;
Guojun TAN
;
Li GUO
- Publication Type:Journal Article
- Keywords:
Brucellosis;
Central nervous system bacterial infections;
Magnetic resonance imaging;
Retrospective studies
- From:
Chinese Journal of Neurology
2014;47(7):482-486
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical features,laboratory tests,imaging characteristics of neurobrucellosis,and to improve the understanding of the disease.Methods A retrospective analysis was performed in seven patients with neurobrucellosis in our hospital from January 2002 to May 2013.Results The proportion of men and women was 6∶ 1,and the average age was 46 years.One case was attacked with the symptoms of cerebrovascular disease,another one with the symptoms of myelitis,and the other five with the symptoms of meningoencephalitis.Six had positive results of serum agglutination test,and the other one had a positive result of blood culture instead.Imaging findings lacked of specificity.There were two patients whose lesions were in the hemisphere cortex,subcortical,basal ganglia and other parts,four patients whose lesions were in the frontal lobe,one in the chest pulp,and one in both sides of cerebellum and pons.After systematical treatment,one case died,the other 6 cases recovered,and no one relapsed or got functional disability during the one-year follow-up.Conclusions Neurobrucellosis is a rare type of brucellosis,and its clinical manifestations lack of specificity,and imaging and serological detections are important for diagnosis.It is beneficial for patients if diagnosed early and treated systematically,so good understanding of this disease,early diagnosis and treatment are of great value.
