Transplantation of en-bloc kidneys and single kidney from pediatric donors to pediatric recipients: 11 cases report

VernacularTitle:婴幼儿供肾儿童肾移植11例报道
Author: Liang ZHU ; Wenyu ZHAO ; Li ZENG ; Lei ZHANG ; Fanyuan ZHU ; Youhua ZHU
Publication Type:Journal Article
Keywords: Kidney transplantation; Child; Donors
From: Chinese Journal of Organ Transplantation 2014;35(5):287-289
CountryChina
Language:Chinese
Abstract: Objective To investigate the therapeutic principle of en-bloc kidney and single kidney transplantation from pediatric donors to pediatric recipients.Method A retrospective analysis of 11 pediatric kidney transplants into pediatric recipients was performed.The age of donors and recipients was 33 days to 48 months,and (9.1 ± 3.4) years (4.6 14.3 years) respectively.Result During the follow-up period of 1 to 22 months,the patient survival rate was 100％.Complications included delayed graft function in 1 case (managed by peritoneal dialysis),urine leak in 2 cases (treated by reoperation),hydronephrosis in 2 cases (treated by extracting ureteral catheter) and vascular thrombosis in 1 case.Due to thrombosis,one graft was lost.Of the remaining 10 recipients,all had excellent long-term function.At the last follow-up,their serum creatinine levels were 65.5 ±13.6 μmol/L (49-83μmol/L),and transplanted renal ultrasound examination showed no abnormality.Conclusion Kidney grafts from pediatric donors can be successfully transplanted to pediatric recipients,but the therapeutic principle is different from that in adult kidney transplantation.