The value of Gd-EOB-DTPA enhanced magnetic resonance imaging in the quantitative evaluation of liver function

VernacularTitle:钆塞酸二钠增强MRI在肝脏功能定量评估中的价值
Author: Lili HUANG ; Zhibin CHENG ; Mei LI ; Yanli JIANG ; Jing ZHANG
Publication Type:Journal Article
Keywords: Liver function; Magnetic resonance imaging; Contrast Media; Gadoxate disodium
From: Chinese Journal of Hepatobiliary Surgery 2014;20(5):324-327
CountryChina
Language:Chinese
Abstract: Objective To explore the value of Gd-EOB-DTPA enhanced magnetic resonance imaging (MRI) in the quantitative evaluation of liver function.Methods Between June 2012 and June 2013,we prospectively included 8 patients with cirrhosis and 6 patients with primary hepatic carcinoma (PHC).The Child-Pugh classification,indocyanine green retention rate at 15 minutes (ICGR15),and Primovist enhanced MR imaging were performed in all the patients.Using the deconvolution method to calculate hepatic extraction fraction (HEF),the correlations between HEF and Child-Pugh and ICGR15 were analyzed.Results For cirrhosis,there was a significant correlation between the HEF and the ICGR15 by the Pearson correlation coefficient (r =-0.971,P ＜ 0.05).For hepatocarcinoma,there was also a significant correlation (r =-0.855,P ＜ 0.05).The average HEF of PHC was 21.80％ (14.89％～ 35.90％).Conclusions The Gd-EOB-DTPA enhanced MRI accurately evaluated liver function quantitatively.It may be used for patients with PHC for preoperative examination.