Tumor associated macrophage in pancreatic cancer
10.3760/cma.j.issn.1007-8118.2014.05.001
- VernacularTitle:胰腺癌中的肿瘤相关巨噬细胞
- Author:
Mengyi WANG
;
Quan LIAO
;
Yupei ZHAO
- Publication Type:Journal Article
- Keywords:
Tumor associated macrophage;
Pancreatic cancer;
Tumor microenvironment
- From:
Chinese Journal of Hepatobiliary Surgery
2014;20(5):321-323
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic cancer is a highly malignant tumor.It is of great importance to improve the effectiveness of treatment by studying the mechanisms which lead to invasion and metastasis in pancreatic cancer.In some malignant tumors,tumor associated macrophage (TAM) plays an important role in tumor progression and invasion.TAM also plays an important role in pancreatic cancer which consists mainly of stromal elements.Research into the mechanisms for occurrence and development of pancreatic cancer,the role played by TAM as well as TAM transformation between the different phenotypes may bring a breakthrough in the treatment of pancreatic cancer.
