Meta-analysis of the influential factors on cervical cancer among married Chinese women in recent 10 years
10.3760/cma.j.issn.1008-6315.2013.13.058
- VernacularTitle:中国近10年已婚妇女宫颈癌发病因素Meta分析
- Author:
Lei WAN
;
Longyu LI
;
Siyuan ZENG
- Publication Type:Journal Article
- Keywords:
Cervical cancer;
Meta-analysis;
Comprehensive analysis
- From:
Clinical Medicine of China
2013;29(z1):133-136
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors of cervical cancer in Chinese married women in recent 10 years in order to provide evidence based approaches for cervical cancer prevention and control Methods Eight case-control studies from 2002 to 2011 were selected from research literatures by using keywords such as cervical cancer, risk factors, influential factors and case-control study, cancer, risk factors, factors andcase-control study as the search term.We adopted the Mentel-Haensel fixed effect model and Dersimonion-Laird random effect model to gain a comprehensive and quantitative assessment of cervical cancer and its risk factors.Results Among the 8 case-control studies,the total number of cases and controls were 2868 and 8045,respectively.The risk factors included human papilloma virus (HPV) (RR =5.47,95 ％ CI:3.40-8.82),family history of cervical cancer (RR =2.40,95 ％ CI:1.39-4.16),number of abortions (RR =1.74,95％ CI:1.49-2.03),first sexual intercourse age number of sexual partners (1.72,95％ CI:1.36-2.16),low cultural level (RR =1.68,95％ CI:1.18-2.40).Conclusion The major risk factors for cervical cancer among married women in China included HPV,family history of cervical cancer,number of abortions,first sexual intercourse age number of sexual partners and low cultural level.
