Magnetic resonance imaging evaluation of Yukatan minipig brains for neurotherapy applications.
10.5625/lar.2011.27.4.309
- Author:
Seung Pil YUN
1
;
Dong Hyun KIM
;
Jung Min RYU
;
Jae Hong PARK
;
Su Shin PARK
;
Ji Hoon JEON
;
Bit Na SEO
;
Hyun Jeong KIM
;
Jun Gyu PARK
;
Kyoung Oh CHO
;
Ho Jae HAN
Author Information
1. Department of Veterinary Physiology, College of Veterinary Medicine, Chonnam National University, Gwangju, Korea.
- Publication Type:Original Article
- Keywords:
Brain;
Yukatan minipigs;
magnetic resonance imaging;
neurologic disorder
- MeSH:
Animals;
Brain;
Head;
Magnetic Resonance Imaging;
Magnetic Resonance Spectroscopy;
Magnetics;
Magnets;
Nervous System Diseases;
Prone Position;
Swine;
Swine, Miniature
- From:Laboratory Animal Research
2011;27(4):309-316
- CountryRepublic of Korea
- Language:English
-
Abstract:
Magnetic resonance imaging (MRI) of six Yukatan minipig brains was performed. The animals were placed in stereotaxic conditions currently used in experiments. To allow for correctpositioning of the animal in the MRI instrument, landmarks were previously traced on the snout of the pig. To avoid movements, animal were anesthetized. The animals were placed in a prone position in a Siemens Magnetom Avanto 1.5 System with a head coil. Axial T2-weighted and sagittal T1-weighted MRI images were obtained from each pig. Afterwards, the brains of the pigs were fixed and cut into axial sections. Histologic and MR images were compared. The usefulness of this technique is discussed.
