The effect of Weifuchun tablet combined with chemotherapy on patients with advanced non-small cell lung cancer
10.3760/cma.j.issn.1008-6706.2014.12.024
- VernacularTitle:胃复春片联合化疗治疗晚期非小细胞肺癌的临床观察
- Author:
Yan GAO
;
Guoliang YAO
;
Yuefeng SHEN
;
Yaming PAN
;
Yi WANG
- Publication Type:Journal Article
- Keywords:
Carcinoma,non-small cell lung;
Medicine,Chinese traditional;
Antineoplastic combined chemotherapy protocols
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;21(12):1814-1816
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical effect of Weifuchun tablet combined with chemotherapy on patients with advanced non-small cell lung cancer (NSCLC).Methods Sixty-eight patients with advanced NSCLC was randomly divided into control group (n =34) treated with cisplatin + gemcitabine and treatment group (n =34) treated with Weifuchun tablet (1.436g × 2/d) and cisplatin + gemcitabine.After two treatment cycles,the clinical effect in both groups were evaluated.Results The clinical efficacy in the treatment group was 52.94％ (18/34),which in the control group was 41.18％ (14/34),there was no statistically significant difference between the two groups(x2 =0.94,P ＞ 0.05).The quality of life and the level of T lymphocytes were markedly improved,and the reduction of hemoglobin,leucocyte,and platelet,and nausea reaction were all significantly inhibited in treatment group compared with that in control group after two treatment cycles (x2 =4.12,4.66,5.96,4.12,5.90,all P ＜ 0.05).Conclusion Weifuchun tablet combined with chemotherapy effectively ameliorates the clinical symptoms of the patient with advanced NSCLC,reduces the toxic and side effects caused by chemotherapy,and improves the quality of life,which is worthy in the clinic.
