Aetiology analysis of pediatric acute leukemia with fungemia
10.3760/cma.j.issn.1008-6706.2014.12.018
- VernacularTitle:儿童急性白血病合并真菌血症病原学分析
- Author:
Jin JIANG
;
Nan LI
;
Jiafeng YAO
- Publication Type:Journal Article
- Keywords:
Leukemia;
Child;
Fungemia;
Blood-borne pathogens
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;21(12):1799-1800
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the epidemiology of fungemia and provide evidence for clinical therapy.Methods A retrospective survey was done with the 42 cases of fungemia in our hospital.Results 42 cases of fungemia include 35 cases acute lymphoid leukemia,6 acute myloid leukemia.95.2% of the fungemia pathogen agent was monilia.8 cases combined with bacterial septicemia,accounting for 19.0%.Drug sensitivity test showed that 2 cases were intermediary to Fluconazole,1 patient was resisdence to Amphotericin B but sensitive to Voriconazole,Itraconazole and fluorocytosine.The main risk factors of fungimia included using wide-spectrum antibiotic,neutophil less than 0.5 × 109/L,central venous indwelling catheter,age and the time of in hospital more than 15 days.Conclusion The effective measure to reduce fungemia morbitity is controlling risk factors.Timely and effectively antifungal therapy is also needed.