Clinical observation of the effect of interferon used for treating bronchiolitis by aerosol inhalation

VernacularTitle:干扰素雾化吸入治疗毛细支气管炎临床疗效观察
Author: Zheng YUAN
Publication Type:Journal Article
Keywords: Interferon-alpha; Adiministration,inhalation; Bronchiolitis; Infant
From: Chinese Journal of Primary Medicine and Pharmacy 2014;21(12):1795-1796
CountryChina
Language:Chinese
Abstract: Objective To study the effect and superiority of interferon used for treating bronchiolitis by aerosol inhalation.Methods 86 patients with bronchiolitis were divided into the two groups,the therapy group with 42 cases,which were received 20μg interferon by aerosol inhalation two daily for 7 days,the control group with 44 cases,which were given 50mag ribavirin by aerosol inhalation two daily for 7 days.The time of asthma and rales disappear in lungs and temperature decresing and hospitalization were observed.Results The time needed for the remission and disappearance of the major symptoms and physical signs like asthma and rales in the therapy group were significantly shorter than those in the control group,there were significant differences between the two groups(t =2.413,2.547,all P ＜0.01).The total effective rates of the therapy group was 88.0％ (37/42),while of the control group was 47.7％ (21/44),there were significant differences(x2 =15.59,P ＜ 0.01),no side effect was found.Conclusion Interferon can be effectively treated bronchiolitis by aerosol inhalation.It is worthy of application.