Clinical value of rapid detection of plasma NT-proBNP levels on admission in patients with acute myocardial infarction
10.3760/cma.j.issn.1008-6706.2014.12.008
- VernacularTitle:急性心肌梗死患者早期快速测定血浆N-末端B型利钠肽原的临床价值
- Author:
Chunde ZHANG
;
Aiping ZHANG
;
Bin CHEN
;
Jiawei LIU
;
Derui HONG
- Publication Type:Journal Article
- Keywords:
Myocardial ischemia;
Peptide hormones
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;21(12):1778-1779
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical prognostic value of rapid detection for plasma NT-proBNP levels on admission in patients with acute myocardial infarction.Methods 56 patients with AMI were measured plasma NT-proBNP imediately in hospital,and then they were divided into A,B and C group according to NT-proBNP levels (A group:＜ 500ng/L,B group:500-2 000ng/L,C group:＞ 2 000ng/L).The incidence of major adverse cardiac events (MACE including congestive heart failure,malignant arrhythmia,cardiogenic shock and sudden cardiac death) in subjects were observed respectively during hospitalisation and 30 days.Results The three group subjects with different NT-proBNP levels presented different incidence of MACE(A group:1,0;B group:3,1;C group:8,6) at duration of hospital stay,30days (x2 =6.705,P =0.035 ; x2 =7.957,P =0.008).With the NT-proBNP levels rising in AMI paitents,the inciedence of MACE increased.The incidence of MACE in A,B and C group were 6.6％,18.18％ and 73.69％ respectively.Conclusion In AMI patients,plasma NT-proBNP levels could predict early MACE incidence,which has an important value to evaluate the early clinical prognosis.
