Evaluation of ray protective agent prevented radiation dermatitis in head carcinoma patients

VernacularTitle:皮肤放疗防护剂预防面颈部放疗引起皮肤损伤的疗效评价
Author: Mengya GE ; Tianbin CHEN
Publication Type:Journal Article
Keywords: Radiodermatitis; Radiotherapy; Radiation-Protective Agents
From: Chinese Journal of Primary Medicine and Pharmacy 2014;21(12):1776-1777
CountryChina
Language:Chinese
Abstract: Objective To evaluate the clinical effects of ray protective agent which prevented radiation dermatitis in head carcinoma patients.Methods 112 patients which prevented radiation dermatitis in head carcinoma patients were divided into the two groups by the single-blind random method.The treated group of 60 patients received the spray of ray protective agent on the radiated skin area 30 min prior and after the radiation exposure with health education,and the control group of 52 patients without any treatment for protection,except health education.The radiation-induced skin damage was observed and the incidence of skin damage was assessed.Results The incidence of 2 and 3 degree skin reaction of the treated group were 15 cases(25.0％) and 4 cases(6.7％),and the incidence of 2 and 3 degree skin reaction of the control group were 21 cases(40.4％) and 28 cases(53.8％),the difference between the two groups had statistical significance(x2 =48.902,24.113,all P ＜ 0.05).Conclusion Ray protective agent is an effective way in reducing the degree of radiation dermatitis,which can relieve pain and improve the quality of life.