Influence of Shensongyangxin capsule on plasma hs-CRP and NT-proBNP in patients with persistent atrial fibrillation after cardioversion
10.3760/cma.j.issn.1008-6706.2014.11.030
- VernacularTitle:参松养心胶囊对持续性心房颤动患者复律后血浆超敏C反应蛋白和N-末端脑钠肽前体水平的影响
- Author:
Zhuxian YU
;
Dongyan LIU
- Publication Type:Journal Article
- Keywords:
Atrial fibrillation;
C-reactive protein;
N-terminal pro-brain natriuretic peptide;
Shensongyangxin capsule
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;21(11):1670-1672
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influence of Shensongyangxin capsule on plasma high-sensitivity C-reactive protein(hs-CRP) and N-terminal pro-brain natriuretic peptide(NT-proBNP) in patients with persistent atrial fibrillation after cardioversion.Methods 152 patients with persistent atrial fibrillation were randomly divided into the observation group(76 cases)and the control group (76 cases).All patients were conducted atrial cardioversion.The patients were followed up for 12 months.The plasma hs-CRP and NT-proBNP were measured before and after treatment.Results All patients with atrial fibrillation were cardioversed to sinus rhythm after cardioversion.During 12 months of follow-up,in the observation group 2 patients had recurrence of atrial fibrillation and in the control group,nine cases of recurrence,the difference between the two groups was significant (x2 =5.28,P ＜ 0.05).After treatment,the plasma hs-CRP and NT-proBNP in the two groups were significantly decreased(t =7.270,3.601,8.118,3.006,P ＜ 0.05,P ＜ 0.01),and those in the observation group were significantly lower than control group (t =4.720,2.914,all P ＜ 0.05).Conclusion Shensongyangxin capsule can significantly reduce plasma hs-CRP and NT-proBNP in patients with persistent atrial fibrillation after cardioversion.
