Clinical analysis of 87 cases of bronchial asthma combined with allergic rhinitis by azelastine hydrochloride nasal spray
- VernacularTitle:联合氮卓斯汀鼻喷剂治疗支气管哮喘合并变应性鼻炎87例临床分析
- Author:
Ping ZHANG
;
He HE
;
Huifang CAO
;
Ying FENG
;
Jianxin DU
;
Ce SHEN
- Publication Type:Journal Article
- Keywords:
Asthma;
Rhinitis,allergic,seasonal;
Azelastine hydrochloride
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(z1):77-79
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of bronchial asthma combined with allergic rhinitis by azelastine hydrochloride nasal spray.Methods Eighty-seven cases of bronchial asthma combined with allergic rhinitis patients were divided into treatment group(45 cases)and control group (42 cases) by random number table method,both groups were given the treatment of bronchial asthma according to the guidelines for regulating,treatment group on the basis was combined with azelastine hydrochloride 1 spray per side,2times per day,for 3 months.Observe two groups of asthma symptoms within 3 months control situation,the number of antibiotics and hospitalization for acute exacerbation.Results Treatment group total effective rate,asthma control test score,number of antibiotics and due to the number of exacerbations hospitalization were superior to control group [93.33％(42/45) vs.76.19％(32/42),(23.80 ± 2.15)scores vs.(22.05 ±3.16) scores,13.3％ (6/45) vs.35.7％ (15/42),11.1％ (5/45) vs.33.3％ (14/42)] (P ＜ 0.05 or ＜ 0.01).Conclusion Combined by azelastine hydrochloride nasal spray may make a good control,reduce the use of antibiotics for acute attack and times of hospitalization,worthy of clinical application.
