Diagnostic value of pulmonary tuberculosis to detect the anti mycobacterium tuberculosis antibody in Serum by the mycobacterium tuberculosis protein Chip and the M.tuberculosis Antibody Colloidal Gold Diagnostic Kit
- VernacularTitle:结核蛋白芯片、结核分枝杆菌抗体胶体金法诊试剂盒检测血清抗结核分枝杆菌抗体对肺结核病的诊断价值探讨
- Author:
Jian HE
;
Qiyun XIANG
;
Jiao WEI
- Publication Type:Journal Article
- Keywords:
Mycobacterium;
Protein chip;
Colloidal gold method;
Antibody
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(z1):53-55
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the Diagnostic value of pulmonary tuberculosis to detecting the anti Mycobacterium tuberculosis antibody with serum samples by the mycobacterium tuberculosis protein Chip and the M.tuberculosis Antibody Colloidal Gold Diagnostic Kit.Methods Application of mycobacterium tuberculosis protein Chip and the M.tuberculosis Antibody Colloidal Gold Diagnostic Kit to detecting the anti Mycobacterium tuberculosis antibody with serum samples,These serum samples are from 110 cases of tuberculosis patients,60 cases of lung disease and 60 cases of healthy people.Results Mycobacterium tuberculosis protein chip sensitivity was 73.6％ (81/110),the specificity was 93.3％ (112/120),the diagnostic kit for detection of Mycobacterium tuberculosis antibody colloidal gold assay sensitivity was 64.5％ (71/110)and a specificity of 91.7％ (110/120),both the sensitivity and specificity compared to no significant difference (P ＞ 0.05).Conclusions The Tuberculosis protein chip and the M.tuberculosis Antibody Colloidal Gold Diagnostic Kit to detect serum Mycobacterium tuberculosis antibodies for diagnosis of TB has a high sensitivity and specificity.Both can be used for the auxiliary diagnosis of tuberculosis.
