Antibiotic resistances of MRSA/MRSE isolated from lower respiratory tract in patients with post-cardiothoracic surgery during the period from 2011-2012
- VernacularTitle:术后下呼吸道耐甲氧西林葡萄球菌感染及耐药监测分析
- Author:
Yuqing CHEN
;
Chun CAI
;
Xin ZHOU
- Publication Type:Journal Article
- Keywords:
Cardiothoracic surgery;
Methicillin-resistance;
Respiratory infection;
Prevention and control
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(z1):1-3
- CountryChina
- Language:Chinese
-
Abstract:
Objective To survey the multi-drug resistance among the isolates of methicillinresistant Staphyloeocus from lower respiratory tract in post-cardiothoracic surgery patients and the risk factors contributing to infection aggravation.Methods The clinical data of lower respiratory tract infections were reviewed retrospectively from June 2011 to December 2012.The antimicrobial susceptibility testing was analyzed according to CLSI breakpoints 2010.Results A total of 323 clinical isolates was identified in 264 patients,including gram-positive coccus (126 strains) and gram-negative bacillus (197 strains).The prevalence of methiciIlin-resistant srtains was 88.5 ％ (54/61)in Staphylococus.Aureus (MRSA),and 77.3％ (17/22) in Staphylococcus epidermidis (MRSE).No VISA or VRSA strain was identified.One enterococcal strain was resistant to Vancomycin and teicoplanin.MRSA/MRSE were also isolated from hands and nasal vestibule of nurses,article surfae,pipeline/interface of breathing machine and ward atmosphere.Conclusions Patients after cardiothoracic operation are susceptible to lower respiratory tract infection with gram positive cocci,which should be paid more attention to airway management.Rational administration,sterile operation and antimicrobial therapy are effective ways for control of multi-durg resistance.
