Risk factors analysis on sepsis complicated with hepatic insufficiency in elder patients
10.3760/cma.j.issn.1673-4904.2014.17.001
- VernacularTitle:老年脓毒症患者并发肝功能不全的危险因素分析
- Author:
Zhixiong WENG
;
Zhijin YU
;
Guoqing LONG
;
Chuyang YE
;
Huixin CHEN
;
Zhihong LIU
- Publication Type:Journal Article
- Keywords:
Aged;
Sepsis;
Hepatic insufficiency;
Risk factors
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(17):1-4
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the risk factors of sepsis complicated with hepatic insufficiency in elder patients.Methods With retrospective case-control study method,according to whether or not complicated with hepatic insufficiency,a total of 384 elder sepsis patients were divided into case group (91 patients) and control group(293 patients),then single factor analysis and multiple factors Logistic regression methods were used to screen the risk factors.Results Single factor analysis identified 6 kinds of significant variables,including age(P =0.000),history of alcohol(P =0.006),chronic diseases(P =0.001),arterial blood lactate level (P =0.035),mechanical ventilation (P =0.009) and acute physiology and chronic health evaluation Ⅲ score (APACHE-Ⅲ) scores(P =0.004).Multiple factors Logistic regression analysis showed that age,history of alcohol,chronic diseases,arterial blood lactate level,mechanical ventilation,APACHE-Ⅲ scores were correlated with sepsis complicated hepatic insuffciency in elder patients (P ＜ 0.01 or ＜ 0.05).Conclusion The risk factors which closely relate to sepsis complicated with hepatic insufficiency in elder patients are age,history of alcohol,chronic diseases,arterial blood lactate level,mechanical ventilation,APACHE-Ⅲ scores.
