Clinical application of ephedrine combined propofol and fentanyl in painless induced abortion
- VernacularTitle:丙泊酚芬太尼复合麻黄碱在无痛人工流产中的应用
- Author:
Xiao WEI
;
Saijuan LIN
;
Shouguo HUANG
;
Guogang TIAN
- Publication Type:Journal Article
- Keywords:
Propofol;
Fentanyl;
Ephedrine;
Induced abortion
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(z1):66-68
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of ephedrine combined propofol and fentanyl in painless induced abortion.Methods Eighty cases of patients (ASA Ⅰ) who apply painless induced abortion were randomly divided into two groups:observation group and control group,each group with 40 cases.Both of the groups were given fentanyl 1 μ g/kg and propofol 2 mg/kg with 2 mg/ml lidocaine; then observation group was given 0.08-0.15 mg/kg ephedrine according to the blood pressure.The heart rate,blood pressure and pulse oximetry (SpO2) of preinduction,3 min and 5 min after induction and 3 min after surgery and the recovery time was observed.Results There was no significant difference about heart rate,blood pressure and SpO2 preinduction,but there was significant difference on 3 min and 5 min after induction in control group in contrast to preinduction [(69.80 ± 7.08),(65.18 ± 5.16) times/min vs.(83.65 ± 8.12)times/min and (86.65 ± 8.60),(90.73 ± 8.35) mmHg (1 mmHg =0.133 kPa) vs.(128.45 ± 11.83) mmHg] (P ＜ 0.05),while observation group kept stable; there was no significant difference about SpO2 and recovery time in both groups.Conclusion It is safe and effective to use ephedrine combined propofol and fentanyl in painless induced abortion.
