The compatibility and adequacy between clinical and hematological standards in the cases with Dengue Haemorrhagic Fever in An Giang in 2002
- Author:
Nguyen Thi Kim Tien
- Publication Type:Journal Article
- Keywords:
Dengue Haemorrhagic Fever;
An Giang;
- MeSH:
Dengue Hemorrhagic Fever;
Dengue;
Diagnosis
- From:Journal of Practical Medicine
2005;517(8):65-69
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
A descriptive prospective study of hospitalized Dengue including Dengue Fever (OF) and Dengue Haemorrhagic Fever (DHF) was undertaken in An Giang General Hospital. An Giang Province from April 2002 to May 2003. A first blood sample (BS) will be taken on admission to detect dengue antibody by Elisa (IgM and IgG) and virus isolation. The second BS will be drawn on discharge with the same test. If the patient is discharged before day 10th after the onset of fever, a third BS will be planned, for IgM and IgG too. In the hospital, all patients will be follow-up adequate platelet count and haematocrit. - There is 1009 patient selected (less than 15 years old), 5 DHF deaths due to DHF and 4 deaths due to others. Classification of the Dengue hospitalized cases: DF (28. 5%), DHF (49%) and DSS (10%). - The highest positive IgM rate is belong to DSS patient group (89%) and then DHF, the lowest rate is DF (34%). The virus isolated rate of the DSS patient group is highest (16.8%), and then DF (14.6%). DEN2 is predominant (with 84% of all virus isolated), and then DEN4 (8.8%). - On the admission, there are the overload for Dengue diagnosis. 12% cases with DF/DHF on the admission but they are typhoid fever, measles and viral infection on the discharge. - Clinical and laboratory findings are the more severe (thrombocytopenia and haemoconcentration), the more positive IgM rate and virus isolated. - For the correspondences between DF, DHF diagnosis. Clinical and laboratory findings according to WHO criteria: there are only 22.2% of DHF satisfied 4/4 WHO criteria, 39.2% satisfied 3/4 criteria and ultrasound is the test supported for these DF, DHF cases. - 71% confirmed DHF cases and 26% confirmed DSS cases have not thrombocytopenia and haemoconcentration. - The haemorrhagic manifestation just appear in 46.6% of DHF cases, even if DSS cases, there are only 56.2% cases have got the haemorrhagic manifestations.
