Medium and long-term therapeutic results of percutaneous transhepatic angioplasty for portal vein stenosis following pediatric liver transplantation
10.3760/cma.j.issn.2095-428X.2014.07.020
- VernacularTitle:小儿肝移植术后门静脉狭窄球囊扩张治疗的中长期结果
- Author:
Haijun GAO
;
Guang CHEN
;
Hao WANG
;
Lianfang WEN
;
Yixin YANG
;
Penghui WANG
- Publication Type:Journal Article
- Keywords:
Pediatric liver transplantation;
Portal vein stenosis;
Interventional radiology;
Percutaneous transluminal angiography
- From:
Chinese Journal of Applied Clinical Pediatrics
2014;29(7):554-557
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the medium and long-term therapeutic results of percutaneous transhepatic angioplasty for portal vein stenosis (PSV) following pediatric liver transplantation.Methods From Jan.2008 to Dec.2012,5 cases with PVS after pediatric liver transplantation received percutaneous transhepatic angioplasty.There were 3 male and 2 female cases ranging from 7 months to 8 year-old with the median age of 2 years and 10 months.The protopathy included 1 Carolis disease and 4 congenital biliary atresia.The therapeutic results were monitored by clinical follow-up and imaging examination.The clinical data,imaging examination and therapeutic results were analyzed.Results All interventions were performed successfully,and the treatment efficacy was 100％.One patient was diagnosed with earl-onset PVS at 0.5 month after liver transplantation.Four patients were diagnosed with late-onset PVS at 3-30 months after liver transplantation.The prestenotic portal venous average diameter was (2.3 ± 0.6) mm (1.2-3.0 mm),the degrees of stenosis were 70％-95％.The poststenotic portal venous average diameter was (9 ± 1) mm (8-10 mm) (t =32.560,P ＜ 0.05).The prestenotic portal venous average pressure gradient was (11.0 ± 3.2) mmHg (8-16 mmHg),and the poststenotic portal venous pressure gradient was(2.2 ± 1.5) mmHg(0-4.0 mmHg) (t =8.242,P ＜ 0.05).Postoperative follow-up was 10-66 months,the portal veins of all cases were patent,and patency rate was 100％.Conclusions Percutaneous transhepatic stent angioplasty is an effective and safe method for treatment of PVS following liver transplantation.Its medium and long-term patency rates are high.
