Research of mesenchymal stem cells used in organ transplantation
10.3760/cma.j.issn.1673-4203.2014.05.016
- VernacularTitle:间充质干细胞应用于器官移植的研究进展
- Author:
Jinfang LIN
;
Weizhen WU
- Publication Type:Journal Article
- Keywords:
Mesenchymal stem cells;
Kidney transplantation;
Acute rejection;
Review
- From:
International Journal of Surgery
2014;41(5):342-344
- CountryChina
- Language:Chinese
-
Abstract:
Transplantation is regarded as the only therapeutic choice for end-stage organ failure,however,rejection restricted its efficacy after transplantation.MSCs exhibit several desirable characteristics,which may advocate their use in organ transplantation.This includes the capacity to suppress alloreactive and autoimmune T-cell responses,and pro mote a cytokine environment which is likely to be graft protective.This review describes the recent research of MSCs used in organ transplant.