Gastrin and its receptor with gastric carcinoma
10.3760/cma.j.issn.1673-4203.2014.07.019
- VernacularTitle:胃泌素及其受体与胃癌关系的研究进展
- Author:
Chunyun WANG
;
Kankan ZHENG
;
Wenbiao XIE
- Publication Type:Journal Article
- Keywords:
Gastrin;
Gastrin receptor;
Stomach neoplasmas
- From:International Journal of Surgery
2014;41(7):490-494
- CountryChina
- Language:Chinese
-
Abstract:
Gastrin is mainly secreted by the G cells in antrum and the upper part of small intestine.Gastrin receptor distributes in various tissues.Gastrin and its receptor have several functions including regulating cell growth and differentiation,inhibiting apoptosis,promoting cell proliferation,invasion and metastasis.Studies have shown that gastrin and its receptor involve with various cancers occurrence and development.Gastrin and its receptor can be used to diagnosis early gastric cancer,and be used as a potential targets in gastric carcinoma treatment.The relationship of gastrin and its receptor with gastric carcinoma were reviewed in this paper.
