The relationship between IL-10, IL-18 and severe pneumonia
10.3760/cma.j.issn.1673-4408.2014.03.007
- VernacularTitle:细胞因子IL-10、IL-18与重症肺炎的关系
- Author:
Shasha DAI
- Publication Type:Journal Article
- Keywords:
Severe pneumonia;
Interleukin-10;
Interleukin-18
- From:
International Journal of Pediatrics
2014;41(3):243-245
- CountryChina
- Language:Chinese
-
Abstract:
Pneumonia is the primary cause of death in children under five years of age.About 2 million children younger than 5 years die of pneumonia each year worldwide,accounting for 19％ of the total number of deaths.According to the survey in 2008,7％ ～ 13％ of the children with pneumonia are severe pneumonia.Severe pneumonia is a life-threatening disease which needs for intensive care.Cytokine IL-10 is a anti-inflammatory cytokine,and IL-18 is a proinflammatory cytokine,both of them are released by the inflammatory response,and can be involved in severe pneumonia immune-mediated.They are closely related to the occurrence,development and prognosis of severe pneumonia.
