Vitamin D deficiency in septic children
10.3760/cma.j.issn.1673-4408.2014.03.029
- VernacularTitle:维生素D缺乏与儿童脓毒症
- Author:
Suyun QIAN
- Publication Type:Journal Article
- Keywords:
Vitamin D;
Sepsis;
Children
- From:
International Journal of Pediatrics
2014;41(3):324-330
- CountryChina
- Language:Chinese
-
Abstract:
Vitamin D deficiency and sepsis are both worldwide problems with health consequences.The pleiotropic actions of vitamin D might synergistically influence pathogenesis of sepsis.Sepsis is associated with local immune responses to pathogens and the activation of systemic inflammatory pathways,which may be the novel targets of vitamin D activity.Clinical observational trials have found vitamin D deficiency is associated with respiratory infections,critical illness and sepsis.The causal relationship has yet to be clearly defined.
