C-terminal provasopressin measurement and cardiovascular disease
10.3760/cma.j.issn.1009-9158.2014.07.004
- VernacularTitle:和肽素检测与心血管疾病
- Author:
Xuhua SHEN
;
Hongwei LI
;
Wenying MA
- Publication Type:Journal Article
- Keywords:
Glycopeptides;
Cardiovascular diseases;
Biological markers
- From:
Chinese Journal of Laboratory Medicine
2014;37(7):493-496
- CountryChina
- Language:Chinese
-
Abstract:
Copeptin,the C-terminal portion of provasopressin,is a novel neurohormone of the arginine vasopressin (AVP)system,and is known to be co-released with AVP from hypothalamus.As a surrogate marker of the AVP system,copeptin has gradually replaced AVP in several clinical studies largely due to its structural and methodological advantages.Copeptin has been regarded as a marker of non-specific stress response.In recent years,copeptin attracts more and more attention especially in cardiovascular conditions (heart failure and acute coronary syndromes).The present review primarily focuses on copeptin detection,its general advantages,and its potential clinical value in a variety of cardiovascular conditions.