The study on perfusion flow of cardiopulmonary bypass during acute Stanford type A aoritc dissection procedure
10.3760/cma.j.issn.1001-4497.2014.06.007
- VernacularTitle:急性Stanford A型主动脉夹层术中的灌注流量
- Author:
Feng LIU
;
Jing YANG
;
Peiqing DONG
- Publication Type:Journal Article
- Keywords:
Aorta;
Aneurysm,dissection;
Cardiac surgical procedures;
Cerebral protection;
Perfusion flow;
Deep hypothermic circulatory arrest;
Antegrade selective cerebral perfusion
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2014;30(6):338-341
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the reasonable perfusion flow of cardiopulmonary bypass during aortic arch procedure of patients with acute type A aortic dissection.Methods Forty patients suffered from acute Stanford type A aortic dissection had been divided into two groups randomly.Group A named traditional perfusion flow group,group B named modified perfusion flow group.Monitoring cerebral blood flow and cerebral tissue oxygen during deep hyperthermia circulatory arrest and antegrade aelective cerebral perfusion procedure by transcranial doppler(TCD) and near-infrared spectroscopy(NIRS).The concentration of S100 protein and lactic acid was measured at six time point.Results Statistical difference of mean blood flow velocity of MCA had been found between two group 3 min after total flow reperfusion.TOI was more tban 60％ during study in both of groups.S100 protein in group A was significantly higher than group B at T6,T7 and T8.Statistical difference of blood lactic concentration had been found between two groups,(4.88± 1.62) mmol/L in group A,(3.83± 1.48) mmol/L in group B,P ＜ 0.05.Safe consciousness time between two groups was difference,(7.36± 2.86) h in group A and (5.27± 3.11) h in group B,P ＜ 0.05.Conclusion Compared with the traditional perfusion flow,modified perfusion flow can provide sufficient cerebral perfusion and prevent the luxury perfusion.
