A study on donor remnant liver regeneration after right lobe adult living donor liver transplantation
10.3760/cma.j.issn.1007-631X.2014.06.011
- VernacularTitle:成人活体右半肝移植术后供者残肝再生的动态研究
- Author:
Qian JI
;
Zhiqiang CHU
;
Wen SHEN
;
Hong ZHENG
;
Ji QI
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Living donors;
Tomography,X-ray computed;
Liver regeneration
- From:
Chinese Journal of General Surgery
2014;29(6):444-447
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate donor remnant liver regeneration and influencing factors at different stages after right lobe adult living donor liver transplantation (LDLT) using multi-slice spiral computed tomography (MSCT).Methods 68 living donors were included in this study,We did CT volumetric measurement of the liver by using IQQA-Liver workstation.Liver regenerative ratio (LRR) at different stages of donors after LDLT were calculated and compared,correlation coefficient and stepwise regression analysis were calculated.Results The difference between LRRs at different stages after LDLT were significant (F =3.323,P =0.009),there were significant difference between LRR of 7-day and 1-month,3-month (respectively t =-2.065,-2.214,all P ＜ 0.05).The inclusion of middle hepatic vein and donor gender had no influence on LRR (respectively t =0.600,-0.622,1.464,0.926,-1.228,0.624,-0.688,0.131,all P ＞ 0.05).There were negative correlation between the remnant liver volume and LRRs (P ＜ 0.05).Conclusions MSCT is a valid modality to evaluate remnant liver regeneration after LDLT.Most evident remnant liver regeneration occurs in early stage after adult LDLT.
