Protamine Induced Anaphylactic Reaction after Cardiopulmonary Bypass: A case report.
- Author:
Jong Hyun BAEK
1
;
Dong Hyup LEE
;
Sung Sae HAN
;
Jung Cheul LEE
;
Tae Eun JUNG
;
Jang Hoon LEE
Author Information
1. Department of Thoracic & Cardiovascular Surgery, College of Medicine, Yeungnam University, Korea. dhlee@med.yu.ac.kr
- Publication Type:Case Report
- Keywords:
Anaphylaxis;
Protamine;
Drugs
- MeSH:
Anaphylaxis*;
Cardiopulmonary Bypass*;
Female;
Heparin;
Humans;
Microwaves;
Middle Aged;
Mitral Valve;
Protamines
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2004;37(7):606-608
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Anaphylactic reaction to protamine sulfate, which is used widely to reverse the anticoagulative effect of heparin after cardiopulmonary bypass, is very rare. But the result of anaphylactic reaction can be very fatal and the mechanism of it is still not clear. We report a case of severe anaphylactic reaction to protamine sulfate following the replacement of the mitral valve and Maze procedure using microwave in a non-diabetic 57-year-old female patient.
