Analysis of etiological factors for non-ulcer dyspepsia in elderly patients presenting to the emergency department
10.3760/cma.j.issn.0254-9026.2014.06.012
- VernacularTitle:急诊科就诊的老年非溃疡性消化不良患者相关致病因素分析
- Author:
Xiaoyan LUO
;
Yan LU
;
Wei LI
;
Yamei TANG
;
Jianfei FANG
- Publication Type:Journal Article
- Keywords:
Dyspepsia;
Helicobacter pylori;
Anxiety;
Pepsinogens
- From:
Chinese Journal of Geriatrics
2014;33(6):613-615
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify etiological factors for non-ulcer dyspepsia (NUD) in elderly patients presenting to the emergency department.Methods A total of 97 elderly patients with NUD presenting to the emergency department from January 2011 to December 2013 were enrolled in the NUD group and 116 elderly people undergoing annual physical examinations served as the control group.Clinical data,including Helicobacter pylori (HP) infection,unhealthy living habits,anxiety,depression and regular intake,were collected and compared between the two groups.Results Compared with the control group,the NUP group showed a higher HP infection rate [70.1％ (68/97)vs.54.3％ (63/116),x2 =5.565,P＜0.05],a higher incidence of unhealthy living habits (unhealthy dietary habits,smoking,drinking,and lack of regular exercise) (P＜0.05),a higher incidence of suspect anxiety/anxiety and a higher incidence of regular intake [30.9％ (30/97) vs 10.3％ (12/116),x2=14.138,P＜0.05].SerumpepsinogenⅠ(PGⅠ) [(178.7±13.6) μg/L vs.(125.2±10.5)μg/L,t=1.971,P＜0.01] and serum pepsinogen Ⅱ(PG Ⅱ) [(28.8±5.3) μg/L vs.(14.7±3.8)μg/L,t=1.960,P＜0.01] levels were also higher in the elderly NUD patients than in the control group.Conclusions HP infection,unhealthy living habits,anxiety and/or depression,and regular intake are closely associated with NUD in the elderly.Serum PGⅠ and PGⅡ could be used as markers in screening for malignant lesions in elderly patients with dyspepsia.
