Chromium-containing traditional Chinese medicine, Tianmai Xiaoke Tablet improves blood glucose through activating insulin-signaling pathway and inhibiting PTP1B and PCK2 in diabetic rats.
- Author:
Qian ZHANG
;
Xinhua XIAO
;
Ming LI
;
Wenhui LI
;
Miao YU
;
Huabing ZHANG
;
Fan PING
;
Zhixin WANG
;
Jia ZHENG
- Publication Type:Journal Article
- From:
Journal of Integrative Medicine
2014;12(3):162-70
- CountryChina
- Language:English
-
Abstract:
Chromium is an essential mineral that is thought to be necessary for normal glucose homeostasis. Numerous studies give evidence that chromium picolinate can modulate blood glucose and insulin resistance. The main ingredient of Tianmai Xiaoke (TMXK) Tablet is chromium picolinate. In China, TMXK Tablet is used to treat type 2 diabetes. This study investigated the effect of TMXK on glucose metabolism in diabetic rats to explore possible underlying molecular mechanisms for its action.
