A Case of Postpoliomyelitis Muscular Atrophy.
- Author:
Jin Yong CHOI
;
Kyung Duk LEE
;
Oh Sang KWON
;
Byung Kun MIN
;
Je Geun CHI
- Publication Type:Case Report
- MeSH:
Arm;
Biopsy;
Diagnosis, Differential;
Fasciculation;
Humans;
Male;
Motor Neuron Disease;
Poliomyelitis;
Postpoliomyelitis Syndrome*;
Thigh;
Young Adult
- From:Journal of the Korean Neurological Association
1988;6(1):110-115
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A relationship between preceding acute paralytic poliomyelitis and the later development of motor neuron disease has only occasionally been suggested since it was first postulated by Charcot in 1875. The authors recently experienced a 20-year-old male who was considered to have postpoliomyelitis muscular atrophy. We report this case in view of its rarity and necessity of differential diagnosis from other neuromuscular disorders. Clinical presentation included slowly progressive muscle wasting of left thigh for 4 years, mild weakness of left arm and both thigh, intermittent fasciculation, and previous history of acute paralytic poliomyelitis. Electromyographic findings showed fibrillation potentials, positive sharp waves, fasciculations, giant motor unit potentials and reduced interference patterns. Muscle biopsy revealed scattered small angulated fibers, individual myofiber degeneration and mild inflammatory cell infiltration.
