Estimation of sample size and testing power (part 2).
- Author:
Liangping HU
;
Xiaolei BAO
;
Lixin TAO
;
Shiguo ZHOU
;
Xue GUAN
- Publication Type:Journal Article
- From:
Journal of Integrative Medicine
2011;9(11):1185-9
- CountryChina
- Language:English
-
Abstract:
This article introduces definitions of three special tests, namely, non-inferiority test (to verify that the efficacy of the experimental drug is clinically not inferior to that of the positive control drug), equivalence test (to verify that the efficacy of the experimental drug is equivalent to that of the control drug) and superiority test (to verify that the efficacy of the experimental drug is superior to that of the control drug), and methods of sample size estimation under the three different conditions. By specific examples, the article introduces formulas of sample size estimation for the three special tests, and their SAS realization in detail.
