Effects of Astragalus membranaceus and Potentilla discolor mixture on insulin resistance and its related mRNA expressions in KKAy mice with type 2 diabetes.
- Author:
Dongmei ZHANG
;
Lixia LOU
;
Aiming WU
;
Xiying Lü
;
Zhaojuan HU
;
Yanhong ZHANG
;
Hongfang LIU
- Publication Type:Journal Article
- From:
Journal of Integrative Medicine
2012;10(7):821-6
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the effects of Astragalus membranaceus and Potentilla discolor mixture (APM) on insulin resistance (IR) and mRNA expressions of IR-related genes, including phosphatidylinositol 3-kinase (PI3-K), phosphoenolpyruvate carboxykinase (PEPCK) and peroxisome proliferator-activated receptor γ coactivator 1 (PGC1) in KKAy mice with early type 2 diabetes and to explore the gene regulation mechanisms of AMP.
