Related substances in orlistat detected with UPLC-MS/MS.
- Author:
Tingting ZHANG
;
Chen MA
- Publication Type:Journal Article
- From:
Acta Pharmaceutica Sinica
2014;49(3):380-4
- CountryChina
- Language:Chinese
-
Abstract:
The study aims to identify related substances in orlistat pharmaceutical substance from different production technologies. Advanced technologies including UPLC-QTOF-MS and UPLC-QTrap-MS were used and the structures or molecules of 10 kinds of related substances in orlistat were identified. The experimental data were valuable to the quality control and development of orlistat.