Effect of Traditional Chinese Medicine Injections on Allergic Reactions

VernacularTitle:常用中药注射剂致敏性研究
Author: Chonggang HUANG ; Zongcheng MO ; Chaoli LUO ; Min WANG
Publication Type:Journal Article
Keywords: Traditional Chinese medicine injections; passive cutaneous anaphylaxis; allergic reactions; serum total IgE
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(4):886-889
CountryChina
Language:Chinese
Abstract: This study was aimed to investigate allergic reactions of traditional Chinese medicine (TCM) injections, and to determine contents of serum IgE in sensitized animals. The correlation between preceding contents in serum and allergic reactions may be found, in order to offer experimental evidences for advancing the accuracy of anticipa-tion by allergic reactions. Passive cutaneous anaphylaxis (PCA) tests and anaphylactoid reactions were used in a vari-ety of TCM injections. ELISA method was used to determine the content of total serum IgE in sensitized animals. The PCA results of SHL, QKL, YXC, XST, GGS and CHN were negative. The PCA result of CWJ was positive. There was no significant difference for total serum IgE level between the experimental group and the normal saline group in the group of SHL, QKL, YXC, XST, GGS, CHN and CWJ. All TCM injections caused anaphylactoid symp-toms in guinea pigs. It was concluded that all TCM injections can cause allergic reactions in guinea pig. And the al-lergic reactions of TCM injections were not correlated with serum total IgE.