Study of HPV infection in common anus and rectal disease
10.3969/j.issn.1673-4130.2014.09.008
- VernacularTitle:肛门、直肠常见病变中HPV感染的研究
- Author:
Xiaodong LIANG
;
Lili ZHANG
;
Jianxiang GENG
;
Kunlan WU
;
Jinhao ZHANG
;
Jianqiang ZHANG
;
Yahong XUE
;
Hongjing WANG
;
Xue ZHAO
- Publication Type:Journal Article
- Keywords:
Papillomavirus;
genotype;
anus diseases;
rectal diseases
- From:
International Journal of Laboratory Medicine
2014;(9):1107-1109
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the human papilloma virus(HPV) infection in lesion tissues of patients with common anus and rectal disease .Methods Gene amplification combined with gene chip technology were employed to conduct genotyping test in lesion tissue of 566 patients with common anus and rectal disease .Results In lesion tissues of 566 patients with common anus and rectal disease ,the overall HPV infection rate was 32 .86% (186/566) .In male patients ,the overall HPV infection rate ,monopole infection rate and multiple infection rate were 32 .14% (117/364) ,23 .35% (85/364) and 8 .79% (32/364) ,respectively ,which showed no sta-tistically significant difference with female [34 .16% (69/202) ,24 .75% (50/202) and 9 .41% (19/202) ,respectively ] (P>0 .05) . HPV 18 ,16 ,33 ,31 types were the main types of common anus and rectal disease .Conclusion HPV genotyping test of anus and rectum tissues is important for molecular epidemiological studies of HPV infection in anus and rectum .
