Safety of ropinirole in the treatment of Parkinson′s disease
10.3760/cma.j.issn.1671-7368.2014.05.018
- VernacularTitle:罗匹尼罗治疗帕金森病的安全性评价
- Author:
Shuhua LI
;
Wen SU
;
Haibo CHEN
;
Xiangyu ZENG
;
Xiaojie CAI
- Publication Type:Journal Article
- Keywords:
Parkinson′s disease;
Bromocriptine;
Ropinirole
- From:
Chinese Journal of General Practitioners
2014;(5):383-385
- CountryChina
- Language:Chinese
-
Abstract:
To explore the safety of ropinirole in the treatment of Parkinson′s disease( PD).A total of 221 PD patients participated in a multi-center,12-week randomized,bromocriptine-controlled,double-blind, double-dummy and parallel-group trial.The safety was assessed on the basis of adverse reactions , blood pressure,pulse,laboratory parameters and electrocardiography recordings.The incidence of adverse reaction was 34.9%in ropinirole group and 34.8% in bromocriptine group.And the frequency of adverse reactions had no inter-group statistical significance (χ2 =0.000,P=0.995).Ropinirole has an excellent profile of safety in the treatment of Chinese PD patients.
