Amplitude of low-frequency oscillations in heroin dependent individuals:a resting state fMRI study
10.3969/j.issn.1002-1671.2014.05.001
- VernacularTitle:海洛因依赖者大脑自发活动强度变化的低频振幅 fMRI 研究
- Author:
Lina WANG
;
Dongsheng ZHANG
;
Jia ZHU
;
Qiang LI
;
Wei LI
;
Hanyue WANG
;
Jiajie CHEN
;
Yongbin LI
;
Xuejiao YAN
;
Yarong WANG
;
Wei WANG
- Publication Type:Journal Article
- Keywords:
heroin;
resting state;
amplitude of low frequency fluctuation;
functional magnetic resonance imaging
- From:
Journal of Practical Radiology
2014;(5):721-724
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of cerebral local neuronal spontaneous activity between heroin dependent individuals and normal controls.Methods 3.0 T MRI were used for data acquisition,fMRI data were acquired during resting state from 20 male heroin dependent individuals(HD)and 1 5 matched normal controls(NC),and then the difference of amplitude of low frequency fluctuation (ALFF)between groups were analysised.Results Compared with NC,ALFF in rostral cingulated zone(bilateral anteri-or cingulate cortex ,medial prefrontal cortex )was significantly reduced in HD.Conclusion Dysfunction of resting state in RCZ were observed in HD,which may result in cognitive impairment and plays an important role in the transitions from ideas into behav-ior of relapse in addiction.
