Comparison of disease activity score 28-C-reactive protein and disease activity score 28-erythrocyte sedimentation rate in patients with rheumatoid arthritis
10.3760/cma.j.issn.1007-7480.2014.04.009
- VernacularTitle:C反应蛋白和红细胞沉降率计算类风湿关节炎患者28个关节疾病活动指数的差异
- Author:
Chenman QIN
;
Shengyun LIU
;
Lei ZHANG
;
Xin ZHANG
;
Jinyan GUO
;
Yujie HE
- Publication Type:Journal Article
- Keywords:
Arthritis rheumatiod;
C-reactive protein;
Erythrocyte sedimentation rate;
Disease activity score
- From:
Chinese Journal of Rheumatology
2014;18(4):255-258
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the disease activity score (DSA) 28-CRP and DAS28-ESR in patients with rheumatoid arthritis.Methods Two hundred and twenty-two patients were enrolled,and their sex,age,disease duration,swollen joint count,tender joint count,CRP,ESR,visual analogue scale were recorded.DAS28-ESR and DAS28-CRP were calculated and then analyzed by t test and Pearson's correlation test.Results There was a significant linear correlation between DAS28-ESR and DAS28-CRP (P＜0.05),with correlation coefficient of 0.968.Both DAS28-CRP (3.3±1.7) and DAS28-ESR (3.9±1.8) scores presented with normal distribution (P＞0.05),with the peak of the DAS28-CRP left to that of the DAS28-ESR.There was statistically significant difference between these two (P＜0.05).The difference between DAS28-CRP and DAS28-ESR was much higher in female (0.59±0.43) than in male (0.24±0.45,P＜0.05).The difference between DAS28-CRP and DAS28-ESR was not related to age and disease duration.Conclusion Attention should be paid to the assessment score when making the plan of treating to target since there is difference between DAS-28-ESR and DAS-28-CRP.
