The clinical manifestations of olivopontocerebellar atrophy and the diagnostic value of MR
10.3760/cma.j.issn.1673-4904.2014.11.017
- VernacularTitle:橄榄桥脑小脑萎缩的临床表现及MR诊断价值
- Author:
Ye ZHONG
;
Gang WU
;
Jun XU
;
Qingxia ZHAN
;
Xuemei ZHANG
- Publication Type:Journal Article
- Keywords:
Olivopontocerebellar atrophies;
Magnetic resonance imaging;
Cross sign
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(11):45-47
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical manifestations and MR imaging features of olivopontocerebellar atrophy(OPCA).Methods The clinical data and MR findings of 8 patients with OPCA (OPCA group) were retrospectively analyzed,and 75 cases of healthy physical examination people were chosen as control group (they were divided into 21-30 years group,31-40 years group,41-50 years group,51-60 years group,61-70 years group,and 15 cases in each group),all subjects under went pons measurement.Results All 8 patients with OPCA were sporadic cases.The cerebellar symptom,autonomic symptoms and extrapyramidal symptoms were common manifestations.The head MR imaging of OPCA presented with cerebellum and brain stem atrophy,cross sign was the characteristic appearance.Vertical diameter and anteroposterior diameter of the pons in OPCA group patients was (20.63 ± 2.16) and (16.74 ±4.37) mm,compared with control group [(27.14 ±1.73) and (22.28 ± 1.49) mm],there was significant difference (P ＜ 0.01).In control group,vertical diameter and anteroposterior diameter of the pons maximum in 21-30 years group and 31-40 years group,increased with age,the value had been reduced,but there was no significant difference (P ＞ 0.05).Conclusion MR is the first choice for the diagnosis of OPCA,combine with clinical manifestations may improve the diagnostic accuracy.
