Progress on serum tumor biomarkers of endometrial carcinoma
10.3760/cma.j.issn.1673-422X.2014.05.014
- VernacularTitle:子宫内膜癌血清肿瘤标志物研究进展
- Author:
Ruifang CHEN
;
Xin LU
- Publication Type:Journal Article
- Keywords:
Endometrial neoplasms;
Tumor markers,biological;
Serum
- From:
Journal of International Oncology
2014;41(5):364-367
- CountryChina
- Language:Chinese
-
Abstract:
Serum tumor biomarkers are significant for the early diagnosis and treatment,preoperative evaluation,prognosis prediction and relapse surveillance of endometrial carcinoma.Recently,serum CA125 and human epididymal secretory protein 4 are widely recognized as closely related with staging,metastasis and prognosis of endometrial cancer.In addition,the serum miRNAs are characterized by their features of high stability and specificity.Omics studies will be helpful for the general assessment of the initiation and progression of endometrial cancer.Insights into these two aspects will facilitate the identifications of new biomarkers with higher sensitivity and specificity for endometrial carcinoma.