Research progress of tree shrew models of viral hepatitis and modeling strategy
10.3969/j.issn.1005-4847.2014.02.0020
- VernacularTitle:病毒性肝炎树鼩动物模型研究与建模策略
- Author:
Yiquan PANG
;
Yue FENG
;
Xiaomei SUN
;
Li LIU
;
Jiejie DAI
;
Xueshan XIA
- Publication Type:Journal Article
- Keywords:
Viral hepatitis;
Hepatitis B virus;
Hepatitis C virus;
Tree shrews;
Animal model
- From:
Acta Laboratorium Animalis Scientia Sinica
2014;(2):95-110
- CountryChina
- Language:Chinese
-
Abstract:
Viral hepatitis is a major liver disease caused by virus infection .Viral hepatitis is popular in China , mainly caused by hepatitis B and hepatitis C viruses .Experimental animal model is a necessary platform for the research on mechanism of viral infection and pathogenicity , for treatment and vaccine development .Up to date, a great progress in the development of viral hepatitis animal models has been achieved in spite of the most of findings are limited to hepatitis B and C.Here, we summarize the recent findings of viral hepatitis animal models , focusing on the tree shrew animal model and its modeling strategy .
