Comparative evaluation on functions-safety of two TCM healthy foods on sale and discussion of relevant problems
10.3969/j.issn.1671-8348.2014.12.019
- VernacularTitle:两种市售中药保健品功效安全的对比评价及相关问题探讨
- Author:
Xiaoguang WANG
;
Haizhou HUANG
;
Xiu SHEN
;
Xiaoliang ZHOU
;
Wei LONG
;
Yujun YAN
;
Zewei ZHOU
- Publication Type:Journal Article
- Keywords:
drugs,Chinese herbal;
dietary supplements;
benefit-damage index;
low-nutritional model;
evaluation approach
- From:
Chongqing Medicine
2014;(12):1463-1467
- CountryChina
- Language:Chinese
-
Abstract:
Objective To conduct the comparative comprehensive evaluation on the actual healthy effects and safety of two kinds of healthy foods capsule A and B made of Chinese medicinal herbs on sale through the low-nutritional sub-health mice model com-bined with the benefit-damage index-general score(BDI-GS) approach ,and to perform the discussion on the relevant problems a-round healthy foods .Methods The experimental healthy ICR male mice during growth period were fed with maize low-nutritional feed and the mixed feed with 3 doses of 0 .25% ,0 .5% ,0 .75% healthy foods for 12 d and the mice body masses were recorded .Af-ter dissection ,9 items of the organ index and their BDI ,GS and serum biochemical indicators were performed the statistics .Results In the capsule A ,the medium and high dose groups manifested certain health-promoting effect ,while the slight negative effect exis-ted in the low dose group ,which was expressed in the GS values ;but in the capsule B ,3 doses all caused the damage to main internal organs in different degrees ,which was expressed in BDI<1 .0 and GS<9 .0 .Conclusion At present ,despite of possessing similar ingredients ,Chinese medicinal healthy foods in market are of greater differences in intrinsic qualities ,and even partial products have some adverse effect ,the healthy functions and safety are not enough to be fully ensured .Through the systematic evaluation of the BDI-GS system ,the criteria of marketing threshold for healthy foods will be increased so as to enhance their effects and safety level .
