Applicatiton of dexmedetomidine in emergent intratracheal intubation
10.3969/j.issn.1671-8348.2014.11.016
- VernacularTitle:右美托咪啶在急诊气管插管中的应用
- Author:
Yi LUO
;
Zhenyu HUANG
;
Lupei LIU
;
Wenxiong MAO
;
Shanhua HUANG
;
Chunping LONG
- Publication Type:Journal Article
- Keywords:
dexmedetomidine;
emergency room,hospital;
intubation,intratracheal;
adverse reaction
- From:
Chongqing Medicine
2014;(11):1326-1328
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of dexmedetomidine on the intubation reaction during intratracheal intubation in the patients in the emergency department .Methods Fifty adult patients needing emergent tracheal intubation in the emergency de-partment of this hospital were divided into the dexmedetomidine group and the middazolam group ,25 cases in each group .The dexmedetomidine group was given dexmedetomidine(1 μg/kg) before tracheal intubation and the midazolam group was given mid-azolam(0 .1 mg/kg) before tracheal intubation .Results BP and HR during tracheal intubation ,at 1 ,3 min after tracheal intubation in the dexmedetomidine group were significantly decreased compared with the midazolam group (P<0 .05);SpO2 at 1 min before tracheal intubation and during tracheal intubation in the dexmedetomidine group had no statistical difference compared with before drug administration(P>0 .05);SpO2 at 1 min before tracheal intubation and during tracheal intubation in the middazolam group was decreased ,which showed the statistical difference compared with before drug administration (P<0 .05) .Conclusion Dexme-detomidine is more effective than midazolam in alleviating cardiovascular responses during intratracheal intubation ,moreover has no influence on the patient′s respiratory function .
