To Study the Analgesic, Anti-diarrhea and Anti-inflammatory Effects of Wulian Compound Extract
- VernacularTitle:复方乌连提取物镇痛、抗炎、止泻的药效学研究
- Author:
Haiqing LI
;
Guiyuan LV
;
Suhong CHEN
- Publication Type:Journal Article
- Keywords:
Traditional Chinese medicine;
analgesia;
anti-inflammation;
diarrhea relieve
- From:
Journal of Zhejiang Chinese Medical University
2014;(4):456-460
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To study the analgesic, anti-diarrhea and anti-inflammatory effects of Wulian compound extract. [Method] To study the analgesic effect of Wulian compound extract on mice with hot-plate test, writhing test, and formaldehyde stimulation. To study the anti-inflammatory effect of Wulian compound extract by mice ear-swol en induced by xylene and abdominal cavity capil ary Permeability text .To study the anti-diarrhea effect of the Wulian compound extract with the method of diarrhea induced by castor oil and senna. [Results] Wulian compound extract can inhibit the pain caused by high fever, acetic acid and formaldehyde. Inhibit the xylene induced ear swel ing of mice and increase of celiac capil ary permeability induced by acetic acid. At the same time Wulian compound extract can prolong diarrhea latency induced by the senna and castor oil, reduce the frequency of diarrhea. [Conclusion]Compound Wulian extracts have significant antidiarrheal effect, anti-inflammatory, analgesic.
