Integrated intravascular ultrasound and fractional flow reserve to guide single-stent crossover ;technique for left main and bifurcation lesions
10.3969/j.issn.1004-8812.2014.04.005
- VernacularTitle:整合血管内超声和血流储备分数指导左主干分叉病变单支架“骑跨”技术的研究
- Author:
Jian LIU
;
Zhao WANG
;
Weimin WANG
;
Liu YANG
;
Chuanfen LIU
;
Qi LI
;
Yuliang MA
;
Mingyu LU
;
Hong ZHAO
- Publication Type:Journal Article
- Keywords:
Intravascular ultrasound;
Fractional flow reserve;
Bifurcation lesions;
Single stent crossover;
MLA
- From:
Chinese Journal of Interventional Cardiology
2014;(4):225-229
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the Minimum Lumen Area (MLA) and plaque burden(PB) of the left circumlfex (LCX) ostial and the occurrence of myocardial ischemia after a single stent crossover for the treatment of left main (LM) bifurcated lesions. Methods Intravascular ultrasound (IVUS) assessment was performed on 5 patients, each where coronary angiography showed left main bifurcated lesions, and to measure the MLA and PB of the LCX. Following a single stent crossover fractional lfow reserve (FFR) evaluation were performed in all 5 patients to investigate the relationship between the MLA and PB of the LCX ostium and the occurrence of myocardial ischemia. Results The mean MLA of the left main coronary of the 5 patients was (4.99±2.3) mm2 with the minimum lumen diameter (MLD) being (2.26±2.8) mm. The average MLA of the left anterior descending (LAD) ostial or proximal was (4.01±2.0) mm2, mean plaque burden (PB) at the LAD ostial or proximal was (68.15±10.1)%. Average MLA of LCX was (4.94±0.4) mm2 with a plaque burden of (66.00±6.0)%. Single stent crossover technique was used to treat the bifurcated lesions. Among the 5 patients, only 1 of them was treated with a double stent deployment where the LCX ostial FFR was<0.75 (FFR=0.42). The remaining 4 patients showed LCX ostial FFR of>0.75. Conclusions Integrated IVUS and FFR would achieve threshold measurements of MLA at LCX’s ostium which could predict ischemia after one stent strategy.
