Research advances on anatomical and molecular biological study of perineural invasion in pancreatic cancer
10.3760/cma.j.issn.1007-8118.2014.04.021
- VernacularTitle:胰腺癌嗜神经侵袭的解剖和分子生物学研究进展
- Author:
Bingrui WANG
;
Weihua QIU
- Publication Type:Journal Article
- Keywords:
Pancreatic cancer;
Perineural invasion;
Perineural space;
Nerve growth factor;
Tumor microenvironment
- From:
Chinese Journal of Hepatobiliary Surgery
2014;20(4):314-317
- CountryChina
- Language:Chinese
-
Abstract:
The phenomenon of perineural invasion in pancreatic cancer occurs more easily.It can cause pain and tumor recurrence,and result in poor prognosis.The perineural invasion of pancreas cancer is closely related to the anatomical basis of pancreas and nerve tissue as well as the changes in the tumor microenvironment.Multiple factors in the microenvironment take part in the development of perineural invasion,meanwhile,the tumor tissue itself can also change the microenvironment.This article is to overview the research on the anatomy and molecular biology of perineural invasion of pancreas cancer.
