An epidemiological survey of nosocomial infections in Chinese patients with active rheumatoid arthritis in Shanghai
- VernacularTitle:上海市活动性类风湿关节炎患者医院感染的流行病学调查
- Author:
Weilin XIE
;
Jianlong GUAN
- Publication Type:Journal Article
- Keywords:
active rheumatoid arthritis;
nosocomial infection;
pathogen;
antibiotic;
antibacterial resistance
- From:
Chinese Journal of Infection and Chemotherapy
2014;(2):135-141
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the incidence,pathogens and clinical features of nosocomial infections in patients with ac-tive rheumatoid arthritis (RA).Methods A total of 2 452 active RA patients were reviewed and analyzed retrospectively in Shanghai hospitals between January 2009 and February 2011.The demographic and clinical characteristics were described.Re-sults A total of 721 episodes of infection were found in 503 patients (20.51%).About 40.97% of the infections were of respir-atory tract,22.35% of urinary tract,and 8.58% of skin and soft tissues.Major pathogens were bacteria (623,86.40%),in-cluding E.coli (226,31.35%),P .aeruginosa (40,5.55%),A.baumannii (48,5.42%),Enterococcus (144,16.25%), methicillin-resistant Staphylococcus aureus (15, 2.08%), methicillin-resistant coagulase-negative Staphylococcus (7, 0.97%).The other pathogens included fungi (74,10.26%),herpes zoster (16,2.21%),and Mycobacterium tuberculosis (8,1.10%).Conclusions Nosocomial infection is mainly seen in respiratory and urinary tracts,usually associated with E.co-li,P .aeruginosa,A.baumanii,methicillin-resistant Staphylococcus and Enterococcus .
